Skip Navigation

NAR Top Articles - Molecular Biology

Molecular Biology

View all categories

May 2016


Nuclear domain 'knock-in' screen for the evaluation and identification of small molecule enhancers of CRISPR-based genome editing
Pinder, Jordan; Salsman, Jayme; Dellaire, Graham
Nucleic Acids Res. 2015, 43, 9379-9392
Free Full Text

Development of an intein-mediated split-Cas9 system for gene therapy
Truong, Dong-Jiunn Jeffery; Kuehner, Karin; Kuehn, Ralf; Werfel, Stanislas; Engelhardt, Stefan; Wurst, Wolfgang; Ortiz, Oskar
Nucleic Acids Res. 2015, 43, 6450-6458
Free Full Text

A cytoplasmic pathway for gapmer antisense oligonucleotide-mediated gene silencing in mammalian cells
Castanotto, Daniela; Lin, Min; Kowolik, Claudia; Wang, LiAnn; Ren, Xiao-Qin; Soifer, Harris S.; Koch, Troels; Hansen, Bo Rode; Oerum, Henrik; Armstrong, Brian; Wang, Zhigang; Bauer, Paul; Rossi, John; Stein, C. A.
Nucleic Acids Res. 2015, 43, 9350-9361
Free Full Text

Rolling circle replication requires single-stranded DNA binding protein to avoid termination and production of double-stranded DNA
Ducani, C; Bernardinelli, G; Hogberg, B
Nucleic Acids Res. 2014, 42, 10596-10604
Free Full Text

Foreign DNA acquisition by the I-F CRISPR–Cas system requires all components of the interference machinery
Vorontsova, D; Datsenko, KA; Medvedeva, S; Bondy-Denomy, J; Savitskaya, EE; Pougach, K; Logacheva, M; Wiedenheft, B; Davidson, AR; Severinov, K; Semenova E
Nucleic Acids Res. 2015, 43, 10848-10860
Free Full Text

Cooperation between SMYD3 and PC4 drives a distinct transcriptional program in cancer cells
Kim, Jin-Man; Kim, Kyunghwan; Schmidt, Thomas; Punj, Vasu; Tucker, Haley; Rice, Judd C.; Ulmer, Tobias S.; An, Woojin
Nucleic Acids Res. 2015, 43, 8868-8883
Free Full Text

A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds
Salvati, Erica; Rizzo, Angela; Iachettini, Sara; Zizza, Pasquale; Cingolani, Chiara; D'Angelo, Carmen; Porru, Manuela; Mondello, Chiara; Aiello, Aurora; Farsetti, Antonella; Gilson, Eric; Leonetti, Carlo; Biroccio, Annamaria
Nucleic Acids Res. 2015, 43, 1759-1769
Free Full Text

Mechanism of CRISPR-RNA guided recognition of DNA targets in Escherichia coli
van Erp, Paul B. G.; Jackson, Ryan N.; Carter, Joshua; Golden, Sarah M.; Bailey, Scott; Wiedenheft, Blake
Nucleic Acids Res. 2015, 43, 8381-8391
Free Full Text

CRISPR interference and priming varies with individual spacer sequences
Xue, C; Seetharam, AS; Musharova, O; Severinov, K; Brouns, SJ; Severin, AJ; Sashital DG
Nucleic Acids Res. 2015, 43, 10831-10847
Free Full Text

Back to the top