Skip Navigation

NAR Top Articles - Nucleic Acid Enzymes

Nucleic Acid Enzymes

View all categories

June 2016


Argonaute of the archaeon Pyrococcus furiosus is a DNA-guided nuclease that targets cognate DNA
Swarts, Daan C.; Hegge, Jorrit W.; Hinojo, Ismael; Shiimori, Masami; Ellis, Michael A.; Dumrongkulraksa, Justin; Terns, Rebecca M.; Terns, Michael P.; van der Oost, John
Nucleic Acids Res. 2015, 43, 5120-5129
Free Full Text

Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
Fonfara, I; Le Rhun, A; Chylinski, K; Makarova, KS; Lecrivain, AL; Bzdrenga, J; Koonin, EV; Charpentier, E
Nucleic Acids Res. 2014, 42, 2577-2590
Free Full Text

Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage
Josephs, Eric A.; Kocak, D. Dewran; Fitzgibbon, Christopher J.; McMenemy, Joshua; Gersbach, Charles A.; Marszalek, Piotr E.
Nucleic Acids Res. 2015, 43, 8924-8941
Free Full Text

mRNA transfection of a novel TAL effector nuclease (TALEN) facilitates efficient knockout of HIV co-receptor CCR5
Mock, Ulrike; Machowicz, Rafal; Hauber, Ilona; Horn, Stefan; Abramowski, Pierre; Berdien, Belinda; Hauber, Joachim; Fehse, Boris
Nucleic Acids Res. 2015, 43, 5560-5571
Free Full Text

Sequence-specific cleavage of dsRNA by Mini-III RNase
Glow, Dawid; Pianka, Dariusz; Sulej, Agata A.; Kozlowski, Lukasz P.; Czarnecka, Justyna; Chojnowski, Grzegorz; Skowronek, Krzysztof J.; Bujnicki, Janusz M.
Nucleic Acids Res. 2015, 43, 2864-2873
Free Full Text

Small RNA-mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylation
Zhang, Guoqiang; Esteve, Pierre-Olivier; Chin, Hang Gyeong; Terragni, Jolyon; Dai, Nan; Correa, Ivan R., Jr.; Pradhan, Sriharsa
Nucleic Acids Res. 2015, 43, 6112-6124
Free Full Text

Binary recombinase systems for high-resolution conditional mutagenesis
Hermann, M; Stillhard, P; Wildner, H; Seruggia, D; Kapp, V; Sanchez-Iranzo, H; Mercader, N; Montoliu, L; Zeilhofer, HU; Pelczar, P
Nucleic Acids Res. 2014, 42, 3894-3907
Free Full Text

The interplay of restriction-modification systems with mobile genetic elements and their prokaryotic hosts
Oliveira, PH; Touchon, M; Rocha, EPC
Nucleic Acids Res. 2014, 42, 10618-10631
Free Full Text

Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase
Chen, Michael C.; Murat, Pierre; Abecassis, Keren; Ferre-D'Amare, Adrian R.; Balasubramanian, Shankar
Nucleic Acids Res. 2015, 43, 2223-2231
Free Full Text

megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
Boissel, S; Jarjour, J; Astrakhan, A; Adey, A; Gouble, A; Duchateau, P; Shendure, J; Stoddard, BL; Certo, MT; Baker, D; Scharenberg, AM
Nucleic Acids Res. 2014, 42, 2591-2601
Free Full Text

Back to the top