Skip Navigation

NAR Top Articles - Nucleic Acid Enzymes

Nucleic Acid Enzymes

View all categories

March 2016


Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage
Josephs, Eric A.; Kocak, D. Dewran; Fitzgibbon, Christopher J.; McMenemy, Joshua; Gersbach, Charles A.; Marszalek, Piotr E.
Nucleic Acids Res. 2015, 43, 8924-8941
Free Full Text


Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
Fonfara, I; Le Rhun, A; Chylinski, K; Makarova, KS; Lecrivain, AL; Bzdrenga, J; Koonin, EV; Charpentier, E
Nucleic Acids Res. 2014, 42, 2577-2590
Free Full Text


A widespread bacteriophage abortive infection system functions through a Type IV toxin-antitoxin mechanism
Dy, RL; Przybilski, R; Semeijn, K; Salmond, GPC; Fineran, PC
Nucleic Acids Res. 2014, 42, 4590-4605
Free Full Text


Sequence-specific cleavage of dsRNA by Mini-III RNase
Glow, Dawid; Pianka, Dariusz; Sulej, Agata A.; Kozlowski, Lukasz P.; Czarnecka, Justyna; Chojnowski, Grzegorz; Skowronek, Krzysztof J.; Bujnicki, Janusz M.
Nucleic Acids Res. 2015, 43, 2864-2873
Free Full Text


The omega subunit of the RNA polymerase core directs transcription efficiency in cyanobacteria
Gunnelius, L; Hakkila, K; Kurkela, J; Wada, H; Tyystjaervi, E; Tyystjaervi, T
Nucleic Acids Res. 2014, 42, 4606-4614
Free Full Text


Binary recombinase systems for high-resolution conditional mutagenesis
Hermann, M; Stillhard, P; Wildner, H; Seruggia, D; Kapp, V; Sanchez-Iranzo, H; Mercader, N; Montoliu, L; Zeilhofer, HU; Pelczar, P
Nucleic Acids Res. 2014, 42, 3894-3907
Free Full Text


megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
Boissel, S; Jarjour, J; Astrakhan, A; Adey, A; Gouble, A; Duchateau, P; Shendure, J; Stoddard, BL; Certo, MT; Baker, D; Scharenberg, AM
Nucleic Acids Res. 2014, 42, 2591-2601
Free Full Text


Replisome mechanics: lagging strand events that influence speed and processivity
Georgescu, RE; Yao, NN; Indiani, C; Yurieva, O; O'Donnell, ME
Nucleic Acids Res. 2014, 42, 6497-6510
Free Full Text


Slicer-independent mechanism drives small-RNA strand separation during human RISC assembly
Park, June Hyun; Shin, Chanseok
Nucleic Acids Res. 2015, 43, 9418-9433
Free Full Text


Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase
Chen, Michael C.; Murat, Pierre; Abecassis, Keren; Ferre-D'Amare, Adrian R.; Balasubramanian, Shankar
Nucleic Acids Res. 2015, 43, 2223-2231
Free Full Text

Back to the top