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NAR Top Articles - Synthetic Biology and Chemistry

Synthetic Biology and Chemistry

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December 2015


Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems
DiCarlo, JE; Norville, JE; Mali, P; Rios, X; Aach, J; Church, GM
Nucleic Acids Res. 2013, 41, 4336-4343
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Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice
Zhou, HB; Liu, B; Weeks, DP; Spalding, MH; Yang, B
Nucleic Acids Res. 2014, 42, 10903-10914
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CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences
Lin, YN; Cradick, TJ; Brown, MT; Deshmukh, H; Ranjan, P; Sarode, N; Wile, BM; Vertino, PM; Stewart, FJ; Bao, G
Nucleic Acids Res. 2014, 42, 7473-7485
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CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity
Cradick, TJ; Fine, EJ; Antico, CJ; Bao, G
Nucleic Acids Res. 2013, 41, 9584-9592
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Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice
Prakash, TP; Graham, MJ; Yu, JH; Carty, R; Low, A; Chappell, A; Schmidt, K; Zhao, CG; Aghajan, M; Murray, HF; Riney, S; Booten, SL; Murray, SF; Gaus, H; Crosby, J; Lima, WF; Guo, SL; Monia, BP; Swayze, EE; Seth, PP
Nucleic Acids Res. 2014, 42, 8796-8807
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A split intein T7 RNA polymerase for transcriptional AND-logic
Schaerli, Y; Gili, M; Isalan, M
Nucleic Acids Res. 2014, 42, 12322-12328
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On the biophysics and kinetics of toehold-mediated DNA strand displacement
Srinivas, N; Ouldridge, TE; Sulc, P; Schaeffer, JM; Yurke, B; Louis, AA; Doye, JPK; Winfree, E
Nucleic Acids Res. 2013, 41, 10641-10658
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A platform for rapid prototyping of synthetic gene networks in mammalian cells
Duportet, X; Wroblewska, L; Guye, P; Li, YQ; Eyquem, J; Rieders, J; Rimchala, T; Batt, G; Weiss, R
Nucleic Acids Res. 2014, 42, 13440-13451
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Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages
Wan, WB; Migawa, MT; Vasquez, G; Murray, HM; Nichols, JG; Gaus, H; Berdeja, A; Lee, S; Hart, CE; Lima, WF; Swayze, EE; Seth, PP
Nucleic Acids Res. 2014, 42, 13456-13468
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Rational optimization of tolC as a powerful dual selectable marker for genome engineering
Gregg, CJ; Lajoie, MJ; Napolitano, MG; Mosberg, JA; Goodman, DB; Aach, J; Isaacs, FJ; Church, GM
Nucleic Acids Res. 2014, 42, 4779-4790
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